| Title: |
Gene expression profiling of mouse liver during a diet of fish oil or olive oil with or without indomethacin. [original title: Gene expression data from mouse liver]
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| Organism(s): |
Mus musculus
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| Description: |
We used microarray analysis to examine which genes are differentially expressed in mice that received a combination of fish oil and indomethacin. We fed low density lipoprotein receptor knock-out (LDLR-/-) mice with 6% of olive oil (control) or fish oil diets in the presence or absence of indomethacin for 12 weeks. We collected total RNA from liver samples and pooled 6 RNA samples in each group for Affymetrix microarrays.
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| Design(s): |
transcription profiling by array
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| Experimental factor(s): |
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| diet
2
recorded
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6% fish oil
6% olive oil
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| organism
1
recorded
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Mus musculus
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| drug
3
recorded
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placebo
indomethacin
indometacin
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| Publication(s): |
Murali G, Milne GL, Webb CD, Stewart AB, McMillan RP, Lyle BC, Hulver MW, Saraswathi V
Fish oil and indomethacin in combination potently reduce dyslipidemia and hepatic steatosis in LDLR(-/-) mice.
PubMed:22847176
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| Sample attribute(s): |
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| Material Type
1
recorded
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|
|
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total RNA
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| experimental period
1
recorded
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|
|
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12 weeks
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| organism part
1
recorded
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|
|
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liver
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| Label
1
recorded
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Biotin
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| genotype
1
recorded
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LDLR-/-
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| organism
1
recorded
|
|
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Mus musculus
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| drug
2
recorded
|
|
|
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control condition
indometacin
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|
| Contact(s): |
Saraswathi Viswanathan Viswanathan Saraswathi
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| Release Date: |
11/6/2012
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| Submission Date: |
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| Metadata Downloads |
Download Study Metadata as ISAtabDownload Study Metadata as ISAtab
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| Assay Downloads |
| transcription profiling using DNA microarray
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| 4 assays |
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