| Title: |
Effects of Inflammation and 5-ASA on ex vivo cultured ulcerative colitis biopsies
|
| Organism(s): |
Homo sapiens
|
| Description: |
To seek effects of inflammatory status and 5-aminosalicylic acid (5-ASA, mesalazine) exposure ex vivo on mRNA levels within rectal mucosal biopsies from patients with ulcerative colitis. A total of 12 biopsies were analysed, 3 biological replicates in each of 4 categories (inflamed with or without 5-ASA, non-inflamed with or without 5-ASA).
|
| Design(s): |
transcription profiling by array
|
| Experimental factor(s): |
|
| inflammation
2
recorded
|
|
|
|
no
yes
|
| compound
4
recorded
|
|
|
|
mesalamine
5-ASA
no drug
control condition
|
|
| Publication(s): |
|
| Sample attribute(s): |
|
| inflammation
2
recorded
|
|
|
|
no
Inflammation of the large intestine
|
| organ
1
recorded
|
|
|
|
rectum
|
| organism part
1
recorded
|
|
|
|
primary culture
|
| tissue
1
recorded
|
|
|
|
colorectal mucosa
|
| Label
1
recorded
|
|
|
|
biotin
|
| disease state
1
recorded
|
|
|
|
ulcerative colitis
|
| organism
1
recorded
|
|
|
|
Homo sapiens
|
|
| Contact(s): |
James Lindsay Rosamond NuamahAndrew SilverAnke NijhuisCharles MeinTammie MacFieCharles MeinTatjana Boitsova
|
| Release Date: |
12/12/2013
|
| Submission Date: |
|
| Metadata Downloads |
Download Study Metadata as ISAtabDownload Study Metadata as ISAtab
|
| Assay Downloads |
| transcription profiling using DNA microarray
|
|
| 12 assays |
|
|
|
|
