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E-GEOD-53851

Title: A probiotics strain attenuating the effects of aspirin in the gut
Organism(s): Mus musculus
Description: Transcriptional profiling of mouse gut after feeding the animals aspirin, teprenone, or Lactobacillus. [original description: Transcriptome analysis of partially degraded and fragmented RNA samples from mus musculus gut Global gene expression profiling has shown the gut transcripts changes through administration of aspirin while probiotics strain administration beforehand attenuates the effect more than teprenone. We analyzed five groups of mice gut using the Affymetrix Mouse Gene 1.0 ST platform. Array data was processed by Affymetrix Exon Array Computational Tool. No technical replicates were performed.]
Design(s): transcription profiling by array
Experimental factor(s):
treatment
5 recorded
Teprenone+Aspirin Lactobacillus gasseri OLL2716+Gum Arabic Lactobacillus gasseri OLL2716+Aspirin Gum Arabic+Aspirin Gum Arabic+Gum Arabic
Publication(s):
Sample attribute(s):
Material Type
1 recorded
total RNA
sex
1 recorded
male
strain
1 recorded
DDY Mouse
age
1 recorded
5 week
organism part
1 recorded
gut
treatment1
3 recorded
teprenone (PubChem CID 5282199) Lactobacillus control condition
Label
1 recorded
biotin
treatment2
1 recorded
acetylsalicylic acid
organism
1 recorded
Mus musculus
Contact(s): Minehiko YokoyamaKimiko AmafujiKimiko AmafujiYoshiko HonmeMisato Soeda
Release Date: 1/7/2014
Submission Date:
Metadata Downloads Download Study Metadata as ISAtabDownload Study Metadata as ISAtab
Assay Downloads
transcription profiling using DNA microarray
5 assays