| Investigation: |
This Study is part of an Investigation, which also includes: GSE11223GSE21274
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| Title: |
Gene expression profiles in synovial biopsies from patients with arthritis
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| Organism(s): |
Homo sapiens
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| Description: |
GeneChip Human Genome U133 Plus 2.0 Arrays (Affymetrix UK Ltd., High Wycombe, UK) were hybridized in monoplicates with 10 g biotinylated cRNA, using synovial biopsy samples obtained in 4 patients with SA [seronegative arthritis, spondylarthritis] (based on the presence of psoriasis or x-ray evidence of sacro-iliacal joint involvement), 5 patients with MIC [microcrystalline arthritis, gout], based on the identification of urate or calcium pyrophosphate crystals in the synovial fluid, 7 patients with RA [rheumatoid arthiritis] (ACR 1987 criteria), 4 patients with SLE [lupus] (ACR criteria) and 5 patients with OA [osteoarthiritis] (based on x-ray evidence of osteoarthritis)
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| Design(s): |
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| Publication(s): |
Nzeusseu Toukap A, Galant C, Theate I, Maudoux AL, Lories RJ, Houssiau FA, Lauwerys BR.
Identification of distinct gene expression profiles in the synovium of patients with systemic lupus erythematosus.
PubMed:17469140
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| Sample attribute(s): |
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| Material Type
1
recorded
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total RNA
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| drug 2
1
recorded
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colchicine
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| sex
2
recorded
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female
male
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| organ
1
recorded
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|
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knee
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| biopsy type
1
recorded
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|
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biopsy
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| age
22
recorded
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|
|
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28 year
51 year
39 year
56 year
55 year
62 year
19 year
38 year
43 year
40 year
52 year
69 year
73 year
65 year
42 year
71 year
72 year
31 year
21 year
47 year
45 year
37 year
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| Label
1
recorded
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Biotin
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| Organism Part
1
recorded
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synovium
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| disease
5
recorded
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spondyloarthropathy
osteoarthritis
gout
rheumatoid arthritis
systemic lupus erythematosus
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| Organism
1
recorded
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Homo sapiens
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| drug
1
recorded
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non-steroidal anti-inflammatory
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| Contact(s): |
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| Release Date: |
3/27/2012
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| Submission Date: |
3/22/2012
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| Metadata Downloads |
Download Study Metadata as ISAtabDownload Study Metadata as ISAtab
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| Assay Downloads |
| transcription profiling using DNA microarray
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| 25 assays |
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