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GSE36700

Investigation: This Study is part of an Investigation, which also includes:GSE11223GSE21274
Title: Gene expression profiles in synovial biopsies from patients with arthritis
Organism(s): Homo sapiens
Description: GeneChip Human Genome U133 Plus 2.0 Arrays (Affymetrix UK Ltd., High Wycombe, UK) were hybridized in monoplicates with 10 g biotinylated cRNA, using synovial biopsy samples obtained in 4 patients with SA [seronegative arthritis, spondylarthritis] (based on the presence of psoriasis or x-ray evidence of sacro-iliacal joint involvement), 5 patients with MIC [microcrystalline arthritis, gout], based on the identification of urate or calcium pyrophosphate crystals in the synovial fluid, 7 patients with RA [rheumatoid arthiritis] (ACR 1987 criteria), 4 patients with SLE [lupus] (ACR criteria) and 5 patients with OA [osteoarthiritis] (based on x-ray evidence of osteoarthritis)
Design(s):
Publication(s): Nzeusseu Toukap A, Galant C, Theate I, Maudoux AL, Lories RJ, Houssiau FA, Lauwerys BR.
Identification of distinct gene expression profiles in the synovium of patients with systemic lupus erythematosus. PubMed:17469140

Sample attribute(s):
Material Type
1 recorded
total RNA
drug 2
1 recorded
colchicine
sex
2 recorded
female male
organ
1 recorded
knee
biopsy type
1 recorded
biopsy
age
22 recorded
28 year 51 year 39 year 56 year 55 year 62 year 19 year 38 year 43 year 40 year 52 year 69 year 73 year 65 year 42 year 71 year 72 year 31 year 21 year 47 year 45 year 37 year
Label
1 recorded
Biotin
Organism Part
1 recorded
synovium
disease
5 recorded
spondyloarthropathy osteoarthritis gout rheumatoid arthritis systemic lupus erythematosus
Organism
1 recorded
Homo sapiens
drug
1 recorded
non-steroidal anti-inflammatory
Contact(s):
Release Date: 3/27/2012
Submission Date: 3/22/2012
Metadata Downloads Download Study Metadata as ISAtabDownload Study Metadata as ISAtab
Assay Downloads
transcription profiling using DNA microarray
25 assays